The Behavioral Reward Affect + Impulsivity Neuroscience (B.R.A.I.N.) Lab at the University of British Columbia is conducting a study to investigate the effectiveness of psilocybin, a serotonergic psychedelic against a placebo with the support of psychotherapy for individuals who struggle with AUD. The information obtained from this research can inform the potential benefits of psychedelic treatments for psychiatric conditions.
Study title: Clairvoyant – Psilocybin Assisted Therapy for Alcohol Use Disorder
Principal Investigator: Dr. Christian Schütz, MD, PhD
Who can participate?
Participants must meet the following criteria in order to participate. Additional criteria may apply.
- Individuals between 19 and 70 years of age.
- Generally healthy with no unstable health conditions.
- Have alcohol dependence and/or use alcohol almost daily and in large amounts.
Additional screening will be completed via phone interview.
What does my participation involve?
The study consists of 13 visits across approximately 29 weeks in a total of 3 periods: Screening Period (up to 5 weeks), Treatment Period (8 weeks) with 2 administration sessions, and a Follow-Up Period (16 weeks). Participation will involve psychotherapy and administration of either psilocybin (25mg) or a placebo.
Purpose of the study:
This phase 2 clinical trial evaluates the safety and efficacy of psilocybin-assisted psychotherapy in adults with Alcohol Use Disorder (AUD) through analysis of alcohol consumption and symptom severity over the 8-week treatment period as compared to baseline.
Eligibility requirements:
Participants must meet the following criteria in order to participate. Additional criteria may apply.
- Individuals between 19 and 70 years of age.
- Generally healthy with no unstable health conditions.
- Have alcohol dependence and/or use alcohol almost daily and in large amounts.
Type of compensation:
Remuneration includes $50 for each visit and $100 for each dosing visit.
How do I get involved?
Please email the research team at brainlab.clairvoyant@ubc.ca. A researcher will contact you to provide additional information about the study and a link to the eligibility questionnaire.