Research interests:
Why sex matters for brain health: impact on hippocampal plasticity, neuropsychiatric and neurodegenerative disorders; Depression and relation to sex and stress hormones; Reproductive experience effects on maternal brain health; How aging impacts neuroplasticity; Adult neurogenesis in the hippocampus and relation to cognition and stress; animal model translation to human disease.

Barha, C.K., Galea, L.A.M. (2011) Motherhood alters the cellular response to estrogens in the hippocampus later in life. Neurobiology of Aging, 32:2091-2095.

Wainwright, S.R., Lieblich, S.E., Galea L.A.M. (2011). Hypogonadism predisposes males to the development of behavioural and neuroplastic depressive phenotypes. Psychoneuroendocrinology 36:1327-1341

Uban, K.A. Rummel, J., Floresco, S.B, Galea, L.A.M. (2012). Estradiol Modulates Effort-Based Decision Making in Female Rats. Neuropsychopharmacology, 37(2):390-401.

Epp, JR., Beasley, C.L.,Galea, L.A.M. (2013). Increased Hippocampal Neurogenesis and p21 Expression in Depression: Dependent on Antidepressants, Sex, Age, and Antipsychotic Exposure. Neuropsychopharmacology, 38:2297-2306.

Chow C, Epp, JR, Lieblich SE, Barha,C.K., Galea, L.A.M. (2013) Sex differences in neurogenesis and activation of new neurons in response to spatial learning Psychoneuroendocrinology, 38, 1236-1250.

Hamson D.K., Wainwright S.R., Taylor J.R., Jones B.A., Watson N.V. , Galea L.A.M. (2013) Androgens Increase Survival of Adult Born Neurons in the Dentate Gyrus by an Androgen Receptor Dependent but Cell Non-Autonomous Mechanism. Endocrinology, 154: 3294-3304.

Galea, L.A.M, Wainwright S.R, Roes, M.M., ,Duarte-Guterman, P., Chow, C. Hamson D.K. (in press, June 2, 2013). Sex, hormones, and neurogenesis in the hippocampus: Hormonal modulation of neurogenesis and potential functional implications. Journal of Neuroendocrinology doi: 10.1111/jne.12070.

Winter 2017

PSYC461 Neuroplasticity and Behaviour Sections

Experimental findings and theory documenting the plasticity of the brain and its relationship to behaviour: emphasis on gene regulation, neurogenesis and cell morphology changes in relation to learning and experience.