Desiree Seib is a postdoctoral fellow supported by the German Research Foundation (DFG), currently working in Dr. Jason Snyder’s lab. During her postdoctoral studies, she has been addressing the role of neurogenesis in pattern separation and depressive-like behaviors. Recently, she received the NARSAD Young Investigator Grant, which provides support for the most promising young scientists conducting neurobiological research. Please join us in congratulating Desiree on this honour!
The goal of her current proposal is to identify the behavioral characteristics of depression that are influenced by adult neurogenesis; specifically, to investigate how reduction of adult hippocampal neurogenesis in a rat model affects behaviors that are altered in depressed human patients. This application builds on her previous work on adult neurogenesis, as well as her experience with transgenic rodent models and rodent behavior.
Seib completed her Ph.D. at the German Cancer Research Center (DKFZ) in Heidelberg, Germany, with a fellowship from the Helmholtz International Graduate School for Cancer Research. During this training, she gained a broad background in Molecular and Cellular Biology as well as expertise in rodent behaviors, including learning and memory and depressive-like behaviors. Since the beginning of her graduate studies, she has been working on the characterization of adult neurogenesis and how it affects behavior. She has investigated adult hippocampal neurogenesis in transgenic mouse models, whose mutations either led to a reduction or an increase in adult-born neuron production in the dentate gyrus. She studied the effects of this increase or reduction of hippocampal neurogenesis, respectively, on cognition and mood. Her work on these two projects was published in two Cell Stem Cell publications (Corsini et al., 2009; Seib et al., 2013).
Learn more about the NARSAD Young Investigator Grant