Exploring the basis of cognitive function and impulse control at a neural, neurochemical and molecular level using rodent analogues of human neuropsychological tests; emphasis on frontostriatal systems, goal-directed behaviour, serotonin, dopamine and noradrenaline.
Winstanley CA, LaPlant Q , Theobald DE , Green TA, Bachtell RK , Perrotti LI , DiLeone RJ, Russo SJ, Garth WJ , Self DW, Nestler EJ (2007) “DeltaFosB induction in orbitofrontal cortex mediates tolerance to cocaine-induced cognitive dysfunction.” Journal of Neuroscience 27: 10497-507.
Winstanley CA, Eagle DM and Robbins TW (2006) “Behavioural models of impulsivity: translation between clinical and preclinical studies” Clinical Psychology Review (4):379-95.
Winstanley CA, Theobald DEH, Dalley JW, Cardinal RN and Robbins TW (2006) “Double dissociation between serotonergic and dopaminergic modulation of medial prefrontal and orbitofrontal cortex during a test of impulsive choice” Cerebral Cortex, 16: 106-14
Winstanley CA, Baunez C, Theobald DEH and Robbins TW (2005) “Lesions to the subthalamic nucleus decrease impulsive choice yet impair autoshaping in rats: the importance of the basal ganglia in Pavlovian conditioning and impulse control” European Journal of Neuroscience 11: 3107-16
Winstanley CA, Dalley, JW, Theobald DEH and Robbins TW (2005) “Interactions between serotonin and dopamine in the control of impulsive choice in rats: therapeutic implications for impulse control disorders” Neuropsychopharmacology 30: 669-82
Winstanley CA, Theobald DEH, Cardinal RN and Robbins TW (2004) “Contrasting roles of basolateral amygdala and orbitofrontal cortex in impulsive choice” Journal of Neuroscience 19: 4718-4722
PSYC361 Motivation Sections
Experimental analysis of hunger, thirst, exploratory and curiosity behaviour, maternal and reproductive behaviour, fixed action patterns, and complex processes involved in social motivation with emphasis on the biological basis of motivation.
One fine body…